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-26.82%Return on Invested Capital
VS
Market
23
Sector
59
Industry
77
History
-
$ 20.97Close
$ 6.07 - $ 27.39 52-Week Range
Ticker Information

Ticker

UPB

Company Name

UPSTREAM BIO INC

Sector

Healthcare

Industry

Biotechnology

Exchange

NASDAQ

UPSTREAM BIO INC - Return on Invested Capital Chart Analysis (TTM)

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UPB - ROIC Historical data
DateInvested CapitalNet Income Common StockReturn on Invested Capital
6/30/2025$ 410.3M$ -110.06M-26.82%
3/31/2025$ 447.31M$ 00%
12/31/2024$ 471.69M$ -76.39M-16.2%
9/30/2024$ -158.37M$ 00%
6/30/2024$ -146.61M$ 00%
12/31/2023$ -123.08M$ -38.26M0%
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Key Performance Insights, Last 5 Years

  • UPSTREAM BIO INC's latest trailing twelve months (TTM) ROIC stands at 0%.
  • Over the past 5 years, UPSTREAM BIO INC's average ROIC has been -21.51%.
  • The median ROIC for UPSTREAM BIO INC during this period was -21.51%
  • UPSTREAM BIO INC reached its highest ROIC over the past 5 years at -16.2%.
  • The lowest ROIC recorded by UPSTREAM BIO INC in the same timeframe -26.82%

UPSTREAM BIO INC's ROIC vs. competitors

We picked the following companies as peers based on multiple factors, including sector, industry, market capitalization and revenue

ROIC Benchmarks
CompanyROIC
ATAI : ATAI LIFE SCIENCES NV -78.07%KALV : KALVISTA PHARMACEUTICALS INC -453.25%VSTM : VERASTEM INC -137.91%LENZ : LENZ THERAPEUTICS INC -25.32%OBIO : ORCHESTRA BIOMED HOLDINGS INC -418.64%QSI : QUANTUM-SI INC -45.86%PYXS : PYXIS ONCOLOGY INC -89.9%NTRB : NUTRIBAND INC -366.06%PGEN : PRECIGEN INC -MLYS : MINERALYS THERAPEUTICS INC -60.84%

Definition of Return on Invested Capital

[Calculation] Return on Invested Capital (ROIC) measures how well a company allocates its invested capital to profitable projects and/or investments. It is calculated as net income [NetIncCmn] divided by invested capital [InvCapital].
Net Inc. Cmn. / Inv. Capital
(=) ROIC
ROIC for UPSTREAM BIO INC is calculated as follows: Net Inc. Cmn. [ $ -38.26M ] / Inv. Capital [ $ -123.08M ]
(=) ROIC [ 0% ]

UPB - Return on Invested Capital, Last 5 years

-26.82%

Minimum

Jun 30, 2025

-16.2%

Maximum

Dec 31, 2024

-21.51%

Average

-21.51%

Median

ROIC Benchmark Analysis

The chart above depicts the distribution of ROIC for companies in the Total Stock Market. The average ROIC of the companies is 0.69% with a standard deviation of 15.18%.
The following table provides additional summary stats:
ROIC in the Market:
filtered constituents3.36K
min-46.36%
max48.66%
average0.69%
median3.38%
std15.18%