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-27.91%Cash Return on Invested Capital
VS
Market
18
Sector
53
Industry
74
History
-
$ 20.97Close
$ 6.07 - $ 27.39 52-Week Range
Ticker Information

Ticker

UPB

Company Name

UPSTREAM BIO INC

Sector

Healthcare

Industry

Biotechnology

Exchange

NASDAQ

UPSTREAM BIO INC - Cash Return on Invested Capital Chart Analysis (TTM)

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UPB - CROIC Historical data
DateCash Return on Invested CapitalFree Cash FlowInvested Capital
6/30/2025-27.91%$ -114.54M$ 410.3M
3/31/20250%$ 0$ 447.31M
12/31/2024-12.65%$ -59.68M$ 471.69M
9/30/20240%$ 0$ -158.37M
6/30/20240%$ 0$ -146.61M
12/31/20230%$ -38.07M$ -123.08M
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Key Performance Insights, Last 5 Years

  • UPSTREAM BIO INC's latest trailing twelve months (TTM) CROIC stands at 0%.
  • Over the past 5 years, UPSTREAM BIO INC's average CROIC has been -20.28%.
  • The median CROIC for UPSTREAM BIO INC during this period was -20.28%
  • UPSTREAM BIO INC reached its highest CROIC over the past 5 years at -12.65%.
  • The lowest CROIC recorded by UPSTREAM BIO INC in the same timeframe -27.91%

UPSTREAM BIO INC's CROIC vs. competitors

We picked the following companies as peers based on multiple factors, including sector, industry, market capitalization and revenue

CROIC Benchmarks
CompanyCROIC
ATAI : ATAI LIFE SCIENCES NV -49.67%KALV : KALVISTA PHARMACEUTICALS INC -375.97%VSTM : VERASTEM INC -99.55%LENZ : LENZ THERAPEUTICS INC -23.15%OBIO : ORCHESTRA BIOMED HOLDINGS INC -358.59%QSI : QUANTUM-SI INC -41.54%PYXS : PYXIS ONCOLOGY INC -68.86%NTRB : NUTRIBAND INC -56.5%PGEN : PRECIGEN INC -MLYS : MINERALYS THERAPEUTICS INC -61.46%

Definition of Cash Return on Invested Capital

[Calculation] Cash Return on Invested Capital (CROIC) measures how well a company uses its invested capital to produce cash. It is calculated as Free Cash Flow [FCF] divided by invested capital [InvCapital].
FCF / Inv. Capital
(=) CROIC
CROIC for UPSTREAM BIO INC is calculated as follows: FCF [ $ -38.07M ] / Inv. Capital [ $ -123.08M ]
(=) CROIC [ 0% ]

UPB - Cash Return on Invested Capital, Last 5 years

-27.91%

Minimum

Jun 30, 2025

-12.65%

Maximum

Dec 31, 2024

-20.28%

Average

-20.28%

Median

CROIC Benchmark Analysis

The chart above depicts the distribution of CROIC for companies in the Total Stock Market. The average CROIC of the companies is 2.78% with a standard deviation of 15.04%.
The following table provides additional summary stats:
CROIC in the Market:
filtered constituents3.46K
min-43.78%
max49.3%
average2.78%
median4.97%
std15.04%